Weitere Publikationen

der Arbeitsgruppe Prof. Dr. Dirk Hoffmeister
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Foto: Janis Fricke
  • 2022
    • Lawrinowitz S, Wurlitzer JM, Weiss D, Arndt, HD, Kothe E, Gressler M, Hoffmeister D (2022) Blue light-dependent pre-mRNA splicing controls pigment biosynthesis in the mushroom Terana caerulea. Microbiol Spectrum 10:e0106522. zur PublikationExterner Link
    • Wurlitzer JM , Stanišić A, Ziethe S, Jordan PM, Günther K, Werz O, Kries H, Gressler M (2022) Macrophage-targeting oligopeptides from Mortierella alpina. Chem Sci 15, 9091-9101. zur PublikationExterner Link
    • Ezediokpu MN, Krause K, Kunert M, Hoffmeister D, Boland W, Kothe E (2022) Ectomycorrhizal influence on the dynamics of sesquiterpene release by Tricholoma vaccinum. J Fungi 24:555. zur PublikationExterner Link
    • Lenz C, Dörner S, Trottmann F, Hertweck C, Sherwood A, Hoffmeister D (2022) Assessment of Bioactivity-Modulating Pseudo-Ring Formation in Psilocin and Related Tryptamine. ChemBioChem 23:e202200183. zur PublikationExterner Link
    • Dörner S, Rogge K, Fricke J, Schäfer T, Wurlitzer JM, Gressler M, Pham DNK, Manke DR, Chadeayne AR, Hoffmeister D (2022) Genetic survey of Psilocybe natural products. ChemBioChem 23:e202200249. zur PublikationExterner Link
    • Löhr NA, Eisen F, Thiele W, Platz L Motter J, Hüttel W, Gressler M, Müller M, Hoffmeister D (2022) Unprecedented Polyketide Synthases Produce the Universal Anthraquinone Precursor. Angew Chem Intl Ed 61:e202116142. zur PublikationExterner Link
    • Kreuzenbeck NB, Seibel E, Schwitalla JW, Fricke J, Schantz-Conlon BH, Schmidt S, Hammerbacher A, Köllner TG, Poulsen M, Hoffmeister D, Beemelmanns CB (2022) Comparative Genomic and Metabolomic Analysis of Termitomyces Species Provides Insights into the Terpenome of the Fungal Cultivar and the Characteristic Odor of the Fungus Garden of Macrotermes natalensis Termites. mSystems 7:e0121421. zur PublikationExterner Link
    • Sonnabend R, Seiler L, Gressler M (2022) Regulation of the Leucine Metabolism in Mortierella alpina. J Fungi 8:196. zur PublikationExterner Link
    • Schäfer T, Kramer K, Werten S, Rupp B, Hoffmeister D (2022) Characterization of the Gateway Decarboxylase for Psilocybin Biosynthesis. ChemBioChem 23:e202200551. zur PublikationExterner Link
  • 2021
    • Herkersdorf S, Krüger T, Wein P, Löffler S, Fontaine T, Gressler M, Hertweck C, Brakhage AA, Hoffmeister D (2021) Bacterial cell wall-degrading enzymes induce basidiomycete natural product biosynthesis. Environ Microbiol 23, 4360-4371. zur PublikationExterner Link
    • Lenz C, Dörner S, Sherwood A, Hoffmeister D (2021) Structure Elucidation and Spectroscopic Analysis of Chromophores Produced by Oxidative Psilocin Dimerization. Chem Eur J 27, 12166-12171. zur PublikationExterner Link
    • Gressler M, Löhr NA, Schäfer T, Lawrinowitz S, Seibold PS, Hoffmeister D (2021) Mind the mushroom: natural product biosynthetic genes and enzymes of Basidiomycota. Nat Prod Rep 38, 702-722. zur PublikationExterner Link
    • Lenz C, Sherwood A, Kargbo R, Hoffmeister D (2021) Taking Different Roads: L-Tryptophan as the Origin of Psilocybe Natural Products. ChemPlusChem 86, 28-35. zur PublikationExterner Link
    • Fricke J, Sherwood AM, Halberstadt AL, Kargbo RB, Hoffmeister D (2021) Chemoenzymatic Synthesis of 5-Methylpsilocybin: A Tryptamine with Potential Psychedelic Activity. J Nat Prod 84, 1403-1408. zur PublikationExterner Link
    • Mohr JF, Baldeweg F, Deicke M, Morales C, Hoffmeister D, Wichard T (2021) Frankobactin Metallophores Produced by Nitrogen-Fixing Frankia Actinobacteria Function in Toxic Metal Sequestration. J Nat Prod 84, 1216-1225. zur PublikationExterner Link
  • 2020
    • Wurlitzer J, Stanišić A, Wasmuth I, Jungmann S, Fischer D, Kries H, Gressler M (2020) Bacterial-like nonribosomal peptide synthetases produce cyclopeptides in the zygomycetous fungus Mortierella alpina. Appl Environ Microbiol 87, e02051-20. zur PublikationExterner Link
    • Lenz C, Wick J, Braga D, García-Altares M, Lackner G, Hertweck C, Gressler M, Hoffmeister D (2020) Injury-Triggered Blueing Reactions of Psilocybe “Magic” Mushrooms. Angew Chem Intl Ed 59, 1450-1454. zur PublikationExterner Link
    • Blei F, Dörner S, Fricke S, Baldeweg F, Trottmann F, Komor A, Meyer F, Hertweck C, Hoffmeister D (2020) Simultaneous production of psilocybin and a cocktail of β-carboline monoamine oxidase inhibitors in ‘magic’ mushrooms. Chem Eur J 26, 729-734. zur PublikationExterner Link
    • Demmler R, Fricke J, Dörner S, Gressler M, Hoffmeister D (2020) S-Adenosyl-L-Methionin Salvage Impacts Psilocybin Formation in 'Magic' Mushrooms. ChemBioChem 21,1364-1371. zur PublikationExterner Link
    • Fricke J, Kargbo R, Regestein L, Lenz C, Peschel G, Rosenbaum M, Sherwood A, Hoffmeister D (2020) Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin. Chem Eur J 26, 8281-8285. zur PublikationExterner Link
    • Seibold PS, Lenz C, Gressler M, Hoffmeister D (2020) The Laetiporus polyketide synthase LpaA produces a series of antifungal polyenes. J Antibiot 73, 711-720. zur PublikationExterner Link
    • Shah F, Gressler M, Nehzati S, Op De Beeck M, Gentile L, Hoffmeister D, Persson P, Tunlid A (2020) Secretion of Iron(III)-Reducing Metabolites during Protein Acquisition by the Ectomycorrhizal Fungus Paxillus involutus. Microorganisms 9, E35. zur PublikationExterner Link
  • 2019
    • König S, Romp E, Krauth V, Rühl M, Dörfer M, Liening S, Hoffmann B, Häfner AK, Steinhilber D, Karas M, Garscha U, Hoffmeister D, Werz O (2019) Melleolides from honey mushroom inhibit 5-lipoxygenase via Cys159. Cell Chem Biol 26, 60-70. zur PublikationExterner Link
    • Baldeweg F, Hoffmeister D, Nett M (2019) A genomics perspective on natural product biosynthesis in plant pathogenic bacteria. Nat Prod Rep 36, 307-325. zur PublikationExterner Link
    • Fricke J, Lenz C, Wick J, Blei F, Hoffmeister D (2019) Production options for psilocybin - The making of the magic. Chem Eur J 25, 897-903. zur PublikationExterner Link
    • Baldeweg F, Warncke P, Fischer D, Gressler M (2019) Fungal Biosurfactants from Mortierella alpina. Org Lett 21, 1444-1448. zur PublikationExterner Link
    • Dörfer M, Heine D, König S, Gore S, Werz O, Hertweck C, Gressler M, Hoffmeister D (2019) Melleolides impact fungal translation via Elongation Factor 2. Org Biomol Chem 17, 4906-4916. zur PublikationExterner Link
    • Fricke J, Sherwood A, Kargbo R, Orry A, Blei F, Naschberger A, Rupp B, Hoffmeister D (2019) Enzymatic route toward 6-methylated baeocystin and psilocybin. ChemBioChem 20, 2824-2829. zur PublikationExterner Link
    • Baccile JA, Le HH, Pfannenstiel B, Bok JW, Gomez C, Brandenburger E, Hoffmeister D, Keller NP, Schroeder FC (2019) Diketopiperazine Formation in Gliotoxin Biosynthesis Requires Dedicated Cyclization and Thiolation Domains. Angew Chem Intl Ed 58, 14589-14593. zur PublikationExterner Link
    • Dörfer M, Gressler, M, Hoffmeister D (2019) Diversity and bioactivity of Armillaria sesquiterpene aryl ester natural products. Mycol Prog 18, 1027-1037.
  • 2018
    • Tauber JP, Gallegos-Monterrosa R, Kovacs AT, Shelest E, Hoffmeister D (2018) Dissimilar pigment regulation in Serpula lacrymans and Paxillus involutus during interkingdom interactions. Microbiology 164, 65-77. zur PublikationExterner Link
    • Tauber JP, Matthaeus C, Lenz C, Hoffmeister D, Popp J (2018) Analysis of basidiomycete pigments in situ by Raman spectroscopy. J Biophoton 11, e201700369. zur PublikationExterner Link
    • Brandenburger E, Braga D,  Kombrink A, Lackner G, Gressler J, Künzler M,  Hoffmeister D (2018) Multi-genome analysis identifies functional and phylogenetic diversity of basidiomycete adenylate-forming reductases. Fungal Genet Biol 112, 55-63. zur PublikationExterner Link
    • Blei F, Baldeweg F, Fricke J, Hoffmeister D (2018) Biocatalytic production of psilocybin and derivatives in tryptophan synthase-enhanced reactions. Chem Eur J 24, 10028-10031. zur PublikationExterner Link
    • Hoefgen S, Lin J, Fricke J, Stroe MC, Mattern DJ, Kufs JE, Hortschansky P, Brakhage AA, Hoffmeister D, Valiante V (2018) Facile assembly and fluorescence-based screening method for heterologous expression of biosynthetic pathways in fungi. Metab Eng 48, 44-51. zur PublikationExterner Link
    • Held BW, Hoffmeister D, Blanchette RA (2018) Occurrence of European Tar Spot (Rhytisma acerinum) on Norway Maple causing severe infections in Minnesota. Plant Disease 102, 12.
    • Blei F, Fricke J, Wick J, Slot JC, Hoffmeister D (2018) Iterative L-tryptophan methylation in Psilocybe evolved by sub-domain duplication. Chembiochem 19, 2160-2166. zur PublikationExterner Link
  • 2017
    • Lenz C, Wick J, Hoffmeister D (2017) Identification of N-Methyl-4-hydroxytryptamine (Norpsilocin) as a Psilocybe Natural Product. J Nat Prod 80, 2835-2838. zur PublikationExterner Link
    • Baldeweg F, Kage H, Schieferdecker S, Allen C, Hoffmeister D, Nett M (2017) Structure of ralsolamycin, the inter-kingdom morphogen from the crop plant pathogen Ralstonia solanacearum GMI1000. Org Lett 19, 4868-4871. zur PublikationExterner Link
    • Brandt P, Garcia-Altares M, Nett M, Hertweck C, Hoffmeister D (2017) Induced chemical defense of a mushroom by a double bond-shifting polyene synthase. Angew Chem Intl Ed 56, 5937-5941. zur PublikationExterner Link
    • Braesel J, Fricke J, Schwenk D, Hoffmeister D (2017) Biochemical and genetic basis of orsellinic acid biosynthesis and prenylation in a stereaceous basidiomycete. Fungal Genet Biol 98, 12-19. zur PublikationExterner Link
    • Zhu Y, Mahaney J, Jellison J, Cao J, Gressler J, Hoffmeister D, Goodell B (2017) Fungal variegatic acid and extracellular polysaccharides promote the site specific generation of reactive oxygen species. J Ind Microbiol Biotechnol 44, 329-338. zur PublikationExterner Link
    • Fricke J, Blei F, Hoffmeister D (2017) Enzymatic synthesis of psilocybin. Angew Chem Intl Ed 56, 12352-12355. zur PublikationExterner Link
    • Brandenburger E, Gressler M, Leonhardt R, Lackner G, Habel A, Hertweck C, Brock M, Hoffmeister D (2017) A highly conserved basidiomycete peptide synthetase produces a trimeric hydroxamate siderophore. Appl Environ Microbiol 83, e01478-17. zur PublikationExterner Link
  • 2016
    • Kalb D, Gressler J, Hoffmeister D (2016) Active-Site Engineering Expands the Substrate Profile of the Basidiomycete L-Tryptophan Decarboxylase CsTDC. ChemBioChem 17, 132-136. zur PublikationExterner Link
    • Shah F, Nicolas C, Bentzer J, Ellström M, Smits M, Rineau F, Canbäck B, Floudas D, Carleer R, Lackner G, Braesel J, Hoffmeister D, Henrissat B, Ahrén D, Johansson T, Hibbett DS, Martin F, Persson P, Tunlid A (2016) Ectomycorrhizal fungi decompose litter material using oxidative mechanisms adapted from saprotrophic ancestors. New Phytol 209, 1705-1719. zur PublikationExterner Link
    • Shah F, Schwenk D, Nicolas C, Persson P, Hoffmeister D, Tunlid A (2016) Involutin is a Fe3+ reductant Secreted by the Ectomycorrhizal Fungus Paxillus involutus during Fenton-based Decomposition of Organic Matter. Appl Environ Microbiol 81, 8427-8433. zur PublikationExterner Link
    • Baccile JA, Spraker JE, Le HH, Brandenburger E, Gomez C, Bok JW, Macheleidt J, Brakhage AA, Hoffmeister D, Keller NP, Schroeder FC (2016) Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus. Nat Chem Biol 12, 419-424. zur PublikationExterner Link
    • Schwenk D, Brandt P, Blanchette R, Nett M, Hoffmeister D (2016) Unexpected metabolic versatility in a combined fungal fomannoxin/vibralactone biosynthesis. J Nat Prod 79, 1407-1414. zur PublikationExterner Link
    • Kalb D, Heinekamp T, Schieferdecker S, Nett M, Brakhage AA, Hoffmeister D (2016) An iterative O-methyltransferase catalyzes 1,11-dimethylation of Aspergillus fumigatus fumaric acid amides. ChemBioChem 17, 1813-1817. zur PublikationExterner Link
    • Schlegel M, Münsterkötter M, Güldener U, Bruggmann R, Duo A, Hainaut M, Henrissat B, Sieber CM, Hoffmeister D, Grünig CR (2016) Globally distributed root endophyte Phialocephala subalpina links pathogenic and saprophytic lifestyles. BMC Genomics 17, 1015. zur PublikationExterner Link
    • Braga D, Hoffmeister D, Nett M (2016) A non-canonical peptide synthetase adenylates 3-methyl-2-oxovaleric acid for auriculamide biosynthesis. Beilstein J Org Chem 12, 2766-2770. zur PublikationExterner Link
    • Tauber JP, Schroeckh V, Shelest E, Brakhage AA, Hoffmeister D (2016) Bacteria induce pigment formation in the basidiomycete Serpula lacrymans. Environ Microbiol 18, 5218-5227. zur PublikationExterner Link
  • 2015
    • Braesel J, Götze S, Shah F, Heine D, Tauber J, Hertweck C, Tunlid A, Stallforth P, Hoffmeister D (2015) Three redundant synthetases secure redox-active pigment production in the basidiomycete Paxillus involutus. Chem Biol 22, 1325-1334. zur PublikationExterner Link
    • Kalb D, Heinekamp T, Lackner G, Scharf DH, Dahse H-M, Brakhage AA, Hoffmeister D (2015) Genetic engineering activates biosynthesis of aromatic fumaric acid amides in the human pathogen Aspergillus fumigatus. Appl Environ Microbiol 81, 1594-1600. zur PublikationExterner Link
    • Kalb D, Lackner G, Rappe M, Hoffmeister D (2015) Activity of α-aminoadipate reductase depends on the N-terminally extending domain. Chembiochem 16, 1426-1430. zur PublikationExterner Link
    • Karlsson M, Durling MB, Choi J, Kosawang C, Lackner G, Tzelepis GD, Nygren K, Dubey MK, Kamou N, Levasseur A, Zapparata A, Wang J, Amby DB, Jensen B, Sarrocco S, Panteris E, Lagopodi AL, Pöggeler S, Vannacci G, Collinge DB, Hoffmeister D, Henrissat B, Lee YH, Jensen DF (2015) Insights on the Evolution of Mycoparasitism from the Genome of Clonostachys rosea. Genome Biol Evol 7, 465-480. zur PublikationExterner Link
    • Stadler M, Hoffmeister D (2015) Fungal natural products-the mushroom perspective. Front Microbiol 6, 127. zur PublikationExterner Link
    • Wick J, Heine D, Lackner G, Misiek M, Tauber J, Jagusch H, Hertweck C, Hoffmeister D (2015) A fivefold parallelized biosynthetic process secures chlorination of Armillaria mellea (honey mushroom) toxins. Appl Environ Microbiol 82, 1196-1204. zur PublikationExterner Link
  • 2014
    • Bohnert M, Nützmann HW, Schroeckh V, Horn F, Dahse HM, Brakhage AA, Hoffmeister D (2014) Cytotoxic and antifungal activities of melleolide antibiotics follow dissimilar structure-activity relationships. Phytochemistry 105, 101-108. zur PublikationExterner Link
    • Bohnert M, Scherer O, Wiechmann K, König S, Dahse HM, Hoffmeister D, Werz O (2014) Melleolides induce rapid cell death in human primary monocytes and cancer cells. Bioorg Med Chem 22, 3856-3861. zur PublikationExterner Link
    • Chankhamjon P, Boettger-Schmidt D, Scherlach K, Urbansky B, Lackner G, Kalb D, Dahse HM, Hoffmeister D, Hertweck C (2014) Biosynthesis of the Halogenated Mycotoxin Aspirochlorine in Koji Mold Involves a Cryptic Amino Acid Conversion. Angew Chem Int Ed Engl 53, 13409-13413. zur PublikationExterner Link
    • Hori C, Ishida T, Igarashi K, Samejima M, Suzuki H, Master E, Ferreira P, Ruiz-Dueñas FJ, Held B, Canessa P, Larrondo LF, Schmoll M, Druzhinina IS, Kubicek CP, Gaskell JA, Kersten P, St John F, Glasner J, Sabat G, Splinter BonDurant S, Syed K, Yadav J, Mgbeahuruike AC, Kovalchuk A, Asiegbu FO, Lackner G, Hoffmeister D, Rencoret J, Gutiérrez A, Sun H, Lindquist E, Barry K, Riley R, Grigoriev IV, Henrissat B, Kües U, Berka RM, Martínez AT, Covert SF, Blanchette RA, Cullen D (2014) Analysis of the Phlebiopsis gigantea Genome, Transcriptome and Secretome Provides Insight into Its Pioneer Colonization Strategies of Wood. PLoS Genet 10, e1004759. zur PublikationExterner Link
    • Kalb D, Lackner G, Hoffmeister D (2014) Functional and phylogenetic divergence of fungal adenylate-forming reductases. Appl Environ Microbiol 80, 6175-6183. zur PublikationExterner Link
    • Kreutzer MF, Kage H, Herrmann J, Pauly J, Hermenau R, Müller R, Hoffmeister D, Nett M (2014) Precursor-directed biosynthesis of micacocidin derivatives with activity against Mycoplasma pneumoniae. Org Biomol Chem 12, 113-118. zur PublikationExterner Link
    • Pauly J, Nett M, Hoffmeister D (2014) Ralfuranone is produced by an alternative aryl-substituted γ-lactone biosynthetic route in Ralstonia solanacearum. J Nat Prod 77, 1967-1971. zur PublikationExterner Link
    • Sasso S, Shelest E, Hoffmeister D (2014) Comments on the distribution and phylogeny of type I polyketide synthases and nonribosomal peptide synthetases in eukaryotes. Proc Natl Acad Sci USA 111, E3946. zur PublikationExterner Link
    • Schwenk D, Nett M, Dahse H-M, Horn U, Blanchette RA, Hoffmeister D (2014) Injury-induced biosynthesis of methyl-branched polyene pigments in a white-rotting basidiomycete J Nat Prod 77, 2658-2663. zur PublikationExterner Link
  • 2013
    • Bohnert M, Dahse HM, Gibson DM, Krasnoff S, Hoffmeister D (2013) The fusarin analogue NG-391 impairs transcription in K-562 leukemia cells. Phytochemistry Letters 6, 189-192. zur PublikationExterner Link
    • Elliott CE, Callahan DL, Schwenk D, Nett M, Hoffmeister D, Howlett BJ (2013) A gene cluster responsible for biosynthesis of phomenoic acid in the plant pathogenic fungus, Leptosphaeria maculans. Fungal Genet Biol 53, 50-58. zur PublikationExterner Link
    • Forseth RR, Amaike S, Schwenk D, Affeldt KJ, Hoffmeister D, Schroeder FC, Keller NP (2013) Homologous NRPS-like gene clusters mediate redundant small-molecule biosynthesis in Aspergillus flavus. Angew Chem Int Ed Engl 52, 1590-1594. zur PublikationExterner Link
    • Kage H, Kreutzer MF, Wackler B, Hoffmeister D, Nett M (2013) An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin. Chem Biol 20, 764-771. zur PublikationExterner Link
    • Kalb D, Lackner G, Hoffmeister D (2013) Fungal peptide synthetases – an update on functions and specificity signatures. Fungal Biology Reviews 27, 43-50. (Review) 
    • Lackner G, Bohnert M, Wick J, Hoffmeister D (2013) Assembly of melleolide antibiotics involves a polyketide synthase with cross-coupling activity. Chem Biol 20, 1101-1106. zur PublikationExterner Link
    • Pauly J, Spiteller D, Linz J, Jacobs J, Allen C, Nett M, Hoffmeister D (2013) Ralfuranone thioether production by the plant pathogen Ralstonia solanacearum. Chembiochem 14, 2169-2178. zur PublikationExterner Link
    • Steinchen W, Lackner G, Yasmin S, Schrettl M, Dahse HM, Haas H, Hoffmeister D (2013) Bimodular peptide synthetase SidE produces fumarylalanine in the human pathogen Aspergillus fumigatus. Appl Environ Microbiol 79, 6670-6676. zur PublikationExterner Link
  • 2012
    • Fernandez-Fueyo E, Ruiz-Dueñas FJ, Ferreira P, Floudas D, Hibbett DS, Canessa P, Larrondo LF, James TY, Seelenfreund D, Lobos S, Polanco R, Tello M, Honda Y, Watanabe T, Watanabe T, Ryu JS, San RJ, Kubicek CP, Schmoll M, Gaskell J, Hammel KE, St John FJ, Vanden Wymelenberg A, Sabat G, Splinter BonDurant S, Syed K, Yadav JS, Doddapaneni H, Subramanian V, Lavín JL, Oguiza JA, Perez G, Pisabarro AG, Ramirez L, Santoyo F, Master E, Coutinho PM, Henrissat B, Lombard V, Magnuson JK, Kües U, Hori C, Igarashi K, Samejima M, Held BW, Barry KW, LaButti KM, Lapidus A, Lindquist EA, Lucas SM, Riley R, Salamov AA, Hoffmeister D, Schwenk D, Hadar Y, Yarden O, de Vries RP, Wiebenga A, Stenlid J, Eastwood D, Grigoriev IV, Berka RM, Blanchette RA, Kersten P, Martinez AT, Vicuna R, Cullen D (2012) Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete chrysosporium provide insight into selective ligninolysis. Proc Natl Acad Sci USA 109, 5458-5463. zur PublikationExterner Link
    • Lackner G, Misiek M, Braesel J, Hoffmeister D (2012) Genome mining reveals the evolutionary origin and biosynthetic potential of basidiomycete polyketide synthases. Fungal Genet Biol 49, 996-991003. zur PublikationExterner Link
    • Misiek M, Hoffmeister D (2012) Sesquiterpene aryl ester natural products in North American Armillaria species. Mycol Progress 11, 7-15. zur PublikationExterner Link
    • Olson A, Aerts A, Asiegbu F, Belbahri L, Bouzid O, Broberg A, Canbäck B, Coutinho PM, Cullen D, Dalman K, Deflorio G, van Diepen LT, Dunand C, Duplessis S, Durling M, Gonthier P, Grimwood J, Fossdal CG, Hansson D, Henrissat B, Hietala A, Himmelstrand K, Hoffmeister D, Högberg N, James TY, Karlsson M, Kohler A, Kües U, Lee YH, Lin YC, Lind M, Lindquist E, Lombard V, Lucas S, Lundén K, Morin E, Murat C, Park J, Raffaello T, Rouzé P, Salamov A, Schmutz J, Solheim H, Ståhlberg J, Vélëz H, de Vries RP, Wiebenga A, Woodward S, Yakovlev I, Garbelotto M, Martin F, Grigoriev IV, Stenlid J (2012) Insight into trade-off between wood decay and parasitism from the genome of a fungal forest pathogen. New Phytol 194, 1001-1013. zur PublikationExterner Link
    • Wackler B, Lackner G, Chooi YH, Hoffmeister D (2012) Characterization of the Suillus grevillei quinone synthetase GreA supports a nonribosomal code for aromatic α-keto acids. Chembiochem 13, 1798-1804. zur PublikationExterner Link
  • 2011
    • Baumgartner K, Coetzee MP, Hoffmeister D (2011) Secrets of the subterranean pathosystem of Armillaria. Mol Plant Pathol 12, 515-534. zur PublikationExterner Link
    • Bohnert M, Miethbauer S, Dahse HM, Ziemen J, Nett M, Hoffmeister D (2011) In vitro cytotoxicity of melleolide antibiotics: structural and mechanistic aspects. Bioorg Med Chem Lett 21, 2003-2006. zur PublikationExterner Link
    • Eastwood DC, Floudas D, Binder M, Majcherczyk A, Schneider P, Aerts A, Asiegbu FO, Baker SE, Barry K, Bendiksby M, Blumentritt M, Coutinho PM, Cullen D, de Vries RP, Gathman A, Goodell B, Henrissat B, Ihrmark K, Kauserud H, Kohler A, LaButti K, Lapidus A, Lavin JL, Lee YH, Lindquist E, Lilly W, Lucas S, Morin E, Murat C, Oguiza JA, Park J, Pisabarro AG, Riley R, Rosling A, Salamov A, Schmidt O, Schmutz J, Skrede I, Stenlid J, Wiebenga A, Xie X, Kües U, Hibbett DS, Hoffmeister D, Högberg N, Martin F, Grigoriev IV, Watkinson SC (2011) The plant cell wall-decomposing machinery underlies the functional diversity of forest fungi. Science 333, 762-765. zur PublikationExterner Link
    • Kreutzer MF, Kage H, Gebhardt P, Wackler B, Saluz HP, Hoffmeister D, Nett M (2011) Biosynthesis of a complex yersiniabactin-like natural product via the mic locus in phytopathogen Ralstonia solanacearum. Appl Environ Microbiol 77, 6117-6124. zur PublikationExterner Link
    • Misiek M, Braesel J, Hoffmeister D (2011) Characterisation of the ArmA adenylation domain implies a more diverse secondary metabolism in the genus Armillaria. Fungal Biol 115, 775-781. zur PublikationExterner Link
    • Wackler B, Schneider P, Jacobs JM, Pauly J, Allen C, Nett M, Hoffmeister D (2011) Ralfuranone biosynthesis in Ralstonia solanacearum suggests functional divergence in the quinone synthetase family of enzymes. Chem Biol 18, 354-360. zur PublikationExterner Link
  • 2010 und früher
    • Bohnert M, Wackler B, Hoffmeister D (2010) Spotlights on advances in mycotoxin research. Appl Microbiol Biotechnol 87, 1-7. zur PublikationExterner Link
    • Misiek M, Williams J, Schmich K, Hüttel W, Merfort I, Salomon CE, Aldrich CC, Hoffmeister D (2009) Structure and cytotoxicity of arnamial and related fungal sesquiterpene aryl esters. J Nat Prod 72, 1888-1891. zur PublikationExterner Link
    • Schneider P, Jacobs JM, Neres J, Aldrich CC, Allen C, Nett M, Hoffmeister D (2009) The global virulence regulators VsrAD and PhcA control secondary metabolism in the plant pathogen Ralstonia solanacearum. Chembiochem 10, 2730-2732. zur PublikationExterner Link
    • Misiek M, Hoffmeister D (2008) Processing sites involved in intron splicing of Armillaria natural product genes. Mycol Res 112, 216-224. zur PublikationExterner Link
    • Schneider P, Bouhired S, Hoffmeister D (2008) Characterization of the atromentin biosynthesis genes and enzymes in the homobasidiomycete Tapinella panuoides. Fungal Genet Biol 45, 1487-1496. zur PublikationExterner Link
    • Schneider P, Weber M, Hoffmeister D (2008) The Aspergillus nidulans enzyme TdiB catalyzes prenyltransfer to the precursor of bioactive asterriquinones. Fungal Genet Biol 45, 302-309. zur PublikationExterner Link
    • Bouhired S, Weber M, Kempf-Sontag A, Keller NP, Hoffmeister D (2007) Accurate prediction of the Aspergillus nidulans terrequinone gene cluster boundaries using the transcriptional regulator LaeA. Fungal Genet Biol 44, 1134-1145. zur PublikationExterner Link
    • Hoffmeister D, Keller NP (2007) Natural products of filamentous fungi: enzymes, genes, and their regulation. Nat Prod Rep 24, 393-416. zur PublikationExterner Link
    • Misiek M, Hoffmeister D (2007) Fungal genetics, genomics, and secondary metabolites in pharmaceutical sciences. Planta Med 73, 103-115. zur PublikationExterner Link
    • Schneider P, Weber M, Rosenberger K, Hoffmeister D (2007) A one-pot chemoenzymatic synthesis for the universal precursor of antidiabetes and antiviral bis-indolylquinones. Chem Biol 14, 635-644. zur PublikationExterner Link
    • Bok JW, Hoffmeister D, Maggio-Hall LA, Murillo R, Glasner JD, Keller NP (2006) Genomic mining for Aspergillus natural products. Chem Biol 13, 31-37. zur PublikationExterner Link
    • Chen YH, Wang CC, Greenwell L, Rix U, Hoffmeister D, Vining LC, Rohr J, Yang KQ (2005) Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase. J Biol Chem 280, 22508-22514. zur PublikationExterner Link
    • Luzhetskyy A, Zhu L, Gibson M, Fedoryshyn M, Dürr C, Hofmann C, Hoffmeister D, Ostash B, Mattingly C, Adams V, Fedorenko V, Rohr J, Bechthold A (2005) Generation of novel landomycins M and O through targeted gene disruption. Chembiochem 6, 675-678. zur PublikationExterner Link
    • Dürr C, Hoffmeister D, Wohlert SE, Ichinose K, Weber M, Von Mulert U, Thorson JS, Bechthold A (2004) The glycosyltransferase UrdGT2 catalyzes both C- and O-glycosidic sugar transfers. Angew Chem Int Ed Engl 43, 2962-2965. zur PublikationExterner Link
    • Hoffmeister D, Thorson JS (2004) Mechanistic implications of Escherichia coli galactokinase structure-based engineering. Chembiochem 5, 989-992. zur PublikationExterner Link
    • Hoffmeister D, Weber M, Dräger G, Ichinose K, Dürr C, Bechthold A (2004) Rational saccharide extension by using the natural product glycosyltransferase LanGT4. Chembiochem 5, 369-371. zur PublikationExterner Link
    • Thorson JS, Barton WA, Hoffmeister D, Albermann C, Nikolov DB (2004) Structure-based enzyme engineering and its impact on in vitro glycorandomization. Chembiochem 5, 16-25. zur PublikationExterner Link
    • Hoffmeister D, Dräger G, Ichinose K, Rohr J, Bechthold A (2003) The C-Glycosyltransferase UrdGT2 is unselective toward D- and L-configured nucleotide-bound rhodinoses. J Am Chem Soc 125, 4678-4679. zur PublikationExterner Link
    • Hoffmeister D, Yang J, Liu L, Thorson JS (2003) Creation of the first anomeric D/L-sugar kinase by means of directed evolution. Proc Natl Acad Sci USA 100, 13184-13189. zur PublikationExterner Link
    • Pelzer S, Hoffmeister D, Merfort I, Bechthold A (2003) Procaryotic and eucaryotic cells in biotech production In: Kayser O, Müller R. H. (eds.) Pharmaceutical Biotechnology, Drug Discovery and Clinical Applications pp. 9-33. Wiley-Blackwell. 
    • Rebets Y, Ostash B, Luzhetskyy A, Hoffmeister D, Brana A, Mendez C, Salas JA, Bechthold A, Fedorenko V (2003) Production of landomycins in Streptomyces globisporus 1912 and S. cyanogenus S136 is regulated by genes encoding putative transcriptional activators. FEMS Microbiol Lett 222, 149-153. zur PublikationExterner Link
    • Rix U, Remsing LL, Hoffmeister D, Bechthold A, Rohr J (2003) Urdamycin L: a novel metabolic shunt product that provides evidence for the role of the urdM gene in the urdamycin A biosynthetic pathway of Streptomyces fradiae TU 2717. Chembiochem 4, 109-111. zur PublikationExterner Link
    • Hoffmeister D, Wilkinson B, Foster G, Sidebottom PJ, Ichinose K, Bechthold A (2002) Engineered urdamycin glycosyltransferases are broadened and altered in substrate specificity. Chem Biol 9, 287-295. zur PublikationExterner Link
    • Hoffmeister D, Ichinose K, Bechthold A (2001) Two sequence elements of glycosyltransferases involved in urdamycin biosynthesis are responsible for substrate specificity and enzymatic activity. Chem Biol 8, 557-567. zur PublikationExterner Link
    • Weitnauer G, Mühlenweg A, Trefzer A, Hoffmeister D, Süssmuth RD, Jung G, Welzel K, Vente A, Girreser U, Bechthold A (2001) Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tü57 and production of new antibiotics. Chem Biol 8, 569-581. zur PublikationExterner Link
    • Faust B, Hoffmeister D, Weitnauer G, Westrich L, Haag S, Schneider P, Decker H, Künzel E, Rohr J, Bechthold A (2000) Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tü2717. Microbiology 146, 147-154. zur PublikationExterner Link
    • Hoffmeister D, Ichinose K, Domann S, Faust B, Trefzer A, Dräger G, Kirschning A, Fischer C, Künzel E, Bearden D, Rohr J, Bechthold A (2000) The NDP-sugar co-substrate concentration and the enzyme expression level influence the substrate specificity of glycosyltransferases: cloning and characterization of deoxysugar biosynthetic genes of the urdamycin biosynthetic gene cluster. Chem Biol 7, 821-831. zur PublikationExterner Link
    • Trefzer A, Hoffmeister D, Künzel E, Stockert S, Weitnauer G, Westrich L, Rix U, Fuchser J, Bindseil KU, Rohr J, Bechthold A (2000) Function of glycosyltransferase genes involved in urdamycin A biosynthesis. Chem Biol 7, 133-142. zur PublikationExterner Link